Islamic Azad University - Arak BranchJournal of Solid Mechanics2008-35058420161220Dynamic Simulation and Mechanical Properties of Microtubules781787527023ENMMotamediFaculty of Engineering, University of Shahreza, P. O. Box 86149-56841, Isfahan, IranMMosavi MashhadiDepartment of Mechanical Engineering, University of Tehran, P.O. Box 11365-4563, Tehran, , IranJournal Article20160721This work is conducted to obtain mechanical properties of microtubule. For this aim, interaction energy in alpha-beta, beta-alpha, alpha-alpha, and beta-beta dimers was calculated using the molecular dynamic simulation. Force-distance diagrams for these dimers were obtained using the relation between potential energy and force. Afterwards, instead of each tubulin, one sphere with 55 KDa weight connecting to another tubulin with a nonlinear connection such as nonlinear spring could be considered. The mechanical model of microtubule was used to calculate Young’s modulus based on finite element method. Obtained Young’s modulus has good agreement with previous works. Also, natural frequency of microtubules was calculated based on finite element method.http://jsm.iau-arak.ac.ir/article_527023_f57d0eaef22419b6d6f15827449536a3.pdf